Selected-GenAtlas references | SOURCE | GeneCards | NCBI Gene | Swiss-Prot | Orphanet | Ensembl |
HGNC | UniGene | Nucleotide | OMIM | UCSC |
Home Page |
FLASH GENE |
Symbol | IL36RN | contributors: mct - updated : 26 -08 -20 |
HGNC name | interleukin 36 receptor antagonist |
HGNC id | 15561 |
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Corresponding disease |
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Location | 2q13 Physical location : - | ||
Synonym name | |||
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Synonym symbol(s) | FIL1D, IL1HY1, IL1L1, IL1RP3, MGC29840, UNQ1896/PRO4342, FIL1, FIL1(DELTA), IL1F5 |
DNA |
TYPE | functioning gene |
SPECIAL FEATURE | component of a cluster |
STRUCTURE | 6.00 kb 5 Exon(s) |
text structure | two alternative non coding first exons |
MAPPING | cloned | Y | linked | N | status | confirmed |
Map | cen - IL1A - IL1B - IL1F7 - IL1F9 - IL1RN - IL1F5 - qter |
Authors | Busfield (00) |
regionally located | cluster of IL1related genes |
RNA |
TRANSCRIPTS | type | messenger |
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text | two alternative non coding first exons |
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EXPRESSION |
Type |
tissue |
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cells |
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cell lineage
cell lines
| fluid/secretion
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at STAGE |
physiological period | embryo |
PROTEIN |
PHYSICAL PROPERTIES
STRUCTURE
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motifs/domains
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conjugated | GlycoP , Other |
HOMOLOGY |
interspecies | ortholog to murine Il1f5 |
Homologene |
FAMILY | interleukin 1 cytokine family |
CATEGORY | secretory , signaling cytokine |
SUBCELLULAR LOCALIZATION | extracellular |
basic FUNCTION | |
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CELLULAR PROCESS |
PHYSIOLOGICAL PROCESS | immunity/defense , inflammation |
PATHWAY |
metabolism |
signaling |
a component |
INTERACTION |
DNA |
RNA |
small molecule |
protein | |
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cell & other |
REGULATION |
induced by | phorbol ester (PHA) and lipopolysaccharide (LPS) |
ASSOCIATED DISORDERS |
corresponding disease(s) | GPP |
Susceptibility |
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Variant & Polymorphism other | putative dysregulation of the interleukin-36–interleukin-36Ra signaling pathway may confer a predisposition to common forms of psoriasis |
Candidate gene
Marker
| Therapy target
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ANIMAL & CELL MODELS |