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FLASH GENE
Symbol PML contributors: shn - updated : 21-05-2016
HGNC name promyelocytic leukemia
HGNC id 9113
ANIMAL & CELL MODELS
  • PMLRAR alpha transgenic mice exhibited neutrophil differentiation impairment and acute promyelocytic leukemia
  • Pml–/– mice had smaller brains and hippocampus than Pml+/+ and Pml+/– mice although the overall organization of the brain did not appear to be affected
  • PML-RARA-targeted DNA vaccine induces protective immunity in a mouse model of leukemia