protein
| HDAC1 |
|
HAT |
|
viral transactivator |
|
inhibits NR4A1 (NUR77) mediated transcription |
|
SIRT1 |
|
TOPBP1 |
|
TRIM27 and TRIM69 |
|
C-terminus of ELF4 |
|
Lassa virus Z protein |
|
mTOR |
|
several transcription factors and their coactivators: HIPK2 and EP300 |
|
HIPK2 |
|
Aurora Kinase A (AURKA) |
|
p53 ubiquitin-ligase Mdm2 |
|
Oncoprotein Mdm2 |
|
nucleolar protein L11 |
|
Myc |
|
bonds and augments the transcriptional activities of Aryl hydrocarbon receptor nuclear translocator (ARNT) |
|
cyclin T1 (CCNT1) |
|
Checkpoint protein with FHA and ring finger domains (CHFR) |
|
CREBBP |
|
death-domain associated protein (DAXX) |
|
Eukaryotic translation initiation factor 4E (eIF4E) |
|
involved in the AP-1 complex and can modulate Fos-mediated transcriptional activity |
|
GATA binding protein 2 (GATA2) |
|
Histone deacetylase 1 and 2 (HDAC1, HDAC2) |
|
proline-rich homeodomain protein PRH |
|
inhibitor of SAPK2/p38 mitogen-activated protein kinase |
|
retinoic acid receptor-alpha (RARalpha), c-Ski, N-CoR, mSin3A and tumor suppressor Mad |
|
c-Myb |
|
Interacts and inhibits Nur77-mediated transcription |
|
regulate the subcellular distribution of the retinoblastoma protein (pRb) and the protein phosphatase 1 alpha (PP1a), triggering pRb dephosphorylation |
|
is a transcriptional repressor of NF-kappaB by interacting with RelA/p65 |
|
prostate-apoptosis-response-4 (Par-4) |
|
Transcription factor Sp1 |
|
Serum response factor (SRF) |
|
STAT3, PIC1 |
|
thymine DNA glycosylase (TDG) |
|
Tif1alpha |
|
stabilizes the DNA damage response protein TopBP1 |
|
acts as a transcriptional co-activator with p53 |
|
Ret finger protein (rfp) |
|
Promyelocytic leukemia zinc finger (PLZF) |
|
ring finger protein 36 (RNF36) |
|
ankyrin repeat domain 2 (ANKRD2) |
|
CREB binding protein (CREBBP) |
|
immediate target gene regulated by IRF8 in response to IFNG activation |
|
PML/RARA binds to FAS and blocks FAS-mediated apoptosis in acute promyelocytic leukemia (APL) by forming an apoptotic inhibitory complex with CFLAR |
|
PML and TBX2 act in an autoregulatory loop to control the effective execution of the senescence program 7) |
|
circadian clock regulator that can physically interact with PER2 |
|
PIAS1 regulates the tumor suppressor PML and its oncogenic counterpart PML-RARA |
|
regulates endothelial cell migration, in part, by modulating expression of downstream genes, such as ITGB1 |
|
undergoes ubiquitination-mediated degradation facilitated by an E3 ligase UHRF1 |
|
PML is required for efficient IFNG1-induced MHC II gene transcription through regulation of the class II transactivator (CIITA), and mediates this function through protection of CIITA from proteasomal degradation |
|
AKT1-mediated phosphorylation of KAT6A suppresses the interaction between PML and KAT6A |
|
NDN bound to PIAS1 central domains that are highly conserved among PIAS family proteins and suppressed PIAS1-dependent sumoylation of the substrates STAT1 and PML |
|
NACC1 cooperates with PML protein |
|
accumulation of HIPK2 in nuclear speckles and association with promyelocytic leukemia protein (PML) in response to DNA damage were also dependent on ABL1 activity |
|
CACUL1 is a novel regulator that negatively controls TP53 activity through the regulation of PML SUMOylation |