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FLASH GENE
Symbol FBXO32 contributors: mct - updated : 25-10-2014
HGNC name F-box only protein 32
HGNC id 16731
ANIMAL & CELL MODELS
  • induced in fasted mice
  • mice lacking atrogin-1 failed to degrade Chmp2b, resulting in autophagy impairment, intracellular protein aggregate accumulation, unfolded protein response activation, and subsequent cardiomyocyte apoptosis, all of which increased progressively with age