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FLASH GENE

Symbol

MOV10L1

contributors: mct - updated : 05-07-2022

HGNC name	Mov10l1, Moloney leukemia virus 10-like 1, homolog (mouse)
HGNC id	7201

FLASH GENE DNA RNA EXPRESSION PROTEIN DISORDER ANIMAL & CELL MODELS

ANIMAL & CELL MODELS

	Primary spermatocytes of Mov10l1(-/-) mice show activation of LTR and LINE-1 retrotransposons, followed by cell death, causing male infertility and a complete block of spermatogenesis at early prophase of meiosis I
	Mov10l1 mutant mice exhibit meiotic arrest and male sterility