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FLASH GENE

Symbol

SSX2

contributors: mct/npt - updated : 04-10-2021

HGNC name	synovial sarcoma, X breakpoint 2
HGNC id	11336

FLASH GENE DNA RNA EXPRESSION PROTEIN DISORDER ANIMAL & CELL MODELS

ASSOCIATED DISORDERS

corresponding disease(s)

BSSX

Other morbid association(s)

Type Gene Modification Chromosome rearrangement Protein expression Protein Function tumoral     --over   in hepatocellular carcinoma (Wu 2006) tumoral fusion       fused with SYT (SSXT) in synovial sarcoma with translocation t(X;18)(p11.2;q11.2) (see BSSX) tumoral fusion       SS18-SSX2 fusion oncogene expression characterizes human synovial sarcoma

Susceptibility

Variant & Polymorphism

Candidate gene	mRNA detect circulating HCC cells as adjuvant diagnostic tool and as indicators of recurrence and prognosis (Wu 2006)
Marker
Therapy target

ANIMAL & CELL MODELS