Selected-GenAtlas references	SOURCE	GeneCards	NCBI Gene	Swiss-Prot	Ensembl
	HGNC	UniGene	Nucleotide	OMIM	UCSC

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FLASH GENE

Symbol

CLDN3

contributors: mct/npt - updated : 21-01-2013

HGNC name	claudin 3
HGNC id	2045

FLASH GENE DNA RNA EXPRESSION PROTEIN DISORDER ANIMAL & CELL MODELS

ASSOCIATED DISORDERS

corresponding disease(s)

Other morbid association(s)

Type Gene Modification Chromosome rearrangement Protein expression Protein Function tumoral     --over   in colorectal cancer tumoral     --over   in 90 p100 of ovarian cancers (Huang 2009)

Susceptibility

Variant & Polymorphism

Candidate gene
Marker
Therapy target
	System Type Disorder Pubmed cancer     anti-claudin-3 and -4 bispecific monoclonal antibody shows promise in the development of a diagnostic and therapeutic antibody for cancers cancer digestive colon potential markers and therapy target in colorectal cancer cancer reproductive ovary may be a promising target for antibody-based therapy of ovarian carcinomas cancer reproductive ovary lipidoid-formulated CLDN3 siRNA has potential as a therapeutic for ovarian cancer

ANIMAL & CELL MODELS