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FLASH GENE
Symbol TPD52 contributors: mct/pgu - updated : 08-01-2013
HGNC name tumor protein D52
HGNC id 12005
ASSOCIATED DISORDERS
corresponding disease(s)
Other morbid association(s)
TypeGene ModificationChromosome rearrangementProtein expressionProtein Function
tumoral   amplification    
in breast carcinoma
tumoral     --over  
in prostate carcinoma
tumoral     --over  
overexpressed in testicular germ cell tumours
tumoral     --over  
significantly up-regulated in colorectal cancers
tumoral     --over  
TPD52 overexpression is a favourable independent prognostic marker of potential value in the management of ovarian carcinoma patients
Susceptibility
Variant & Polymorphism
Candidate gene
Marker potential biomarker for prostate cancer
colorectal cancer
Therapy target
SystemTypeDisorderPubmed
cancerreproductiveprostate
regulatory sequence that may be used to restrict expression of therapeutic genes to prostate cancer in the prostate cancer gene therapy
ANIMAL & CELL MODELS