basic FUNCTION
| molecular marker in ovarian cancer |
|
prostate-specific and androgen-responsive gene amplified in prostate cancer |
|
promotes cell proliferation and survival during prostate cancer development and progression |
|
expression is associated with the progression of prostate cancer LNCaP cells and with androgen signals |
|
plays an important role in various molecular events, in the morphological diversification and dissemination of prostate carcinoma cells |
|
directly regulates LAMP1 exocytosis in a phosphorylation-dependent manner |
|
its phosphorylation plays an important role in the vesicle trafficking events that direct cell abscission |
|
Ca2+-dependent phosphorylation at serine 136 plays a mechanistic role in regulating VAMP8-positive endosomal vesicle trafficking necessary for cell abscission during cytokinesis |