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FLASH GENE

Symbol

ADH4

contributors: mct - updated : 09-09-2010

HGNC name	alcohol dehydrogenase 4 (class II), pi polypeptide
HGNC id	252

FLASH GENE DNA RNA EXPRESSION PROTEIN DISORDER ANIMAL & CELL MODELS

ASSOCIATED DISORDERS

corresponding disease(s)

Other morbid association(s)

Type Gene Modification Chromosome rearrangement Protein expression Protein Function constitutional     --over   increased expression of ADH1A and ADH4 in non-alcoholic steatohepatitis livers (baker 2010)

Susceptibility

to alcoholism to cluster headache

Variant & Polymorphism SNP	12SNPs significantly associated to alcoholism
	rs1126671 polymorphism resulted significantly different between cluster headache patients and controls (Rainero 2010)

Candidate gene

Marker

Therapy target

ANIMAL & CELL MODELS