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FLASH GENE

Symbol

BMP3

contributors: mct - updated : 02-02-2008

HGNC name	bone morphogenetic protein 3
HGNC id	1070

FLASH GENE DNA RNA EXPRESSION PROTEIN DISORDER ANIMAL & CELL MODELS

ASSOCIATED DISORDERS

corresponding disease(s)

Other morbid association(s)

Type Gene Modification Chromosome rearrangement Protein expression Protein Function tumoral     --low   in malignant schwannoma tumoral     --low   in colorectal carcinoma, by promoter hypermethylation

Susceptibility

Variant & Polymorphism

Candidate gene
Marker
Therapy target	attractive target for the future development of molecular blood and/or stool screening tests for the early detection of lesions with neoplastic potential

ANIMAL & CELL MODELS

mouse Bmp3-/-have as much trabecular bone as wild type littermates