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FLASH GENE
Symbol MIEN1 contributors: mct - updated : 24-05-2012
HGNC name migration and invasion enhancer 1
HGNC id 28230
ASSOCIATED DISORDERS
corresponding disease(s)
Other morbid association(s)
TypeGene ModificationChromosome rearrangementProtein expressionProtein Function
tumoral     --over  
in infiltrating ductal carcinomas of the breast
tumoral     --over  
  • abundantly expressed in breast cancer, expression positively correlating with grade and stage of cancer progression
  • tumoral     --over  
    in the higher grades of prostate adenocarcinoma compared with low expression in normal or benign prostatic tissues
    Susceptibility
    Variant & Polymorphism
    Candidate gene biomarker and/or a target for development of broadly applicable cancer-specific therapies
    Marker
    Therapy target
    SystemTypeDisorderPubmed
    cancer  
    important target for cancer therapy, since the over expression of MIEN1 functionally enhances migration and invasion of tumor cells
    ANIMAL & CELL MODELS