basic FUNCTION
| cysteine-containing protein that may have a redox function |
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acts as a signaling molecule channeling signaling through PI3K/Akt pathway |
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possible role in metastatic dissemination of cancer cells |
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can use catalytic cysteine (or Sec) to form transient mixed disulfides with substrate proteins |
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acts as a signalling molecule that increases invasive potential of prostate cancer cells by NF-KappaB-mediated downstream target gene |
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functionally enhances migration and invasion of tumor cells and is an important target for cancer therapy |
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prenylation is required for its function in cancer cells and imply that the post-translational modification may functionally regulate metastatic progression of disease |
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role in the migration and metastatic dissemination of cancer cells |