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FLASH GENE
Symbol PLXDC1 contributors: SGE - updated : 26-03-2010
HGNC name plexin domain containing 1
HGNC id 20945
ASSOCIATED DISORDERS
corresponding disease(s)
Other morbid association(s)
TypeGene ModificationChromosome rearrangementProtein expressionProtein Function
tumoral     --over  
highly expressed in osteogenic sarcoma (Fuchs 2007)
Susceptibility
Variant & Polymorphism
Candidate gene
Marker
Therapy target
  • may be a molecular target for new diagnostic and therapeutic strategies for proliferative diabetic retinopathy (Yamaji 2008)
  • elevated expression is associated with metastasis and poor survival of pateints with osteogenic sarcoma and may be a therapeutic target (Fuchs 2007)
  • ANIMAL & CELL MODELS