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FLASH GENE

Symbol

IPO13

contributors: mct/pgu - updated : 25-11-2021

HGNC name	importin 13
HGNC id	16853

FLASH GENE DNA RNA EXPRESSION PROTEIN DISORDER ANIMAL & CELL MODELS

ASSOCIATED DISORDERS

corresponding disease(s)

Other morbid association(s)

Type Gene Modification Chromosome rearrangement Protein expression Protein Function constitutional     --over   significantly increased in the basal layer of the epithelium of the pterygium constitutional       loss of function could lead to ocular coloboma, microphthalmia, and cataract tumoral     --over   in endometriosis and endometrial carcinoma

Susceptibility

to airway hyperresponsiveness in asthmatic children

Variant & Polymorphism other	IPO13 variation is associated with improved airway hyperresponsiveness in asthmatic children

Candidate gene
Marker	can serve as an endometrial progenitor/stem cell marker
Therapy target

ANIMAL & CELL MODELS