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FLASH GENE
Symbol KIF14 contributors: mct - updated : 17-09-2018
HGNC name kinesin family member 14
HGNC id 19181
ASSOCIATED DISORDERS
corresponding disease(s) MCPH20 , MKS12
Other morbid association(s)
TypeGene ModificationChromosome rearrangementProtein expressionProtein Function
tumoral     --over  
in retinoblastoma tumors, primary retinoblastoma with an older age at diagnosis, breast and lung cancer
tumoral     --over  
associated with increased overall survival (OAS) of ovarian cancer patients
tumoral     --over  
in Medulloblastoma (MB) and is an adverse prognostic factor for survival
tumoral     --over  
of KIF14 and E2F3 protein in retinoblastoma
Susceptibility
Variant & Polymorphism
Candidate gene
Marker
  • may represent a novel and useful prognostic biomarker for Prostate carcinoma
  • Therapy target
    SystemTypeDisorderPubmed
    cancerbrain 
    potential therapeutic target for Medulloblastoma (MB)
    ANIMAL & CELL MODELS