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FLASH GENE

Symbol

TRPV3

contributors: mct - updated : 21-03-2018

HGNC name	transient receptor potential cation channel, subfamily V, member 3
HGNC id	18084

FLASH GENE DNA RNA EXPRESSION PROTEIN DISORDER ANIMAL & CELL MODELS

ASSOCIATED DISORDERS

corresponding disease(s)

Other morbid association(s)

Type Gene Modification Chromosome rearrangement Protein expression Protein Function constitutional     --low   in injured brachial plexus nerves

Susceptibility

Variant & Polymorphism

Candidate gene	good candidate for future therapy in skin inflammation and pruritus
Marker
Therapy target
	System Type Disorder Pubmed dermatology skin   targeting TRPV3 could provide therapeutic potential for keratinization or itching-related skin disorders.

ANIMAL & CELL MODELS

	mutation of TRPV3 is linked to defective hair growth and dermatitis in rodents
	mice lacking the Trpv3 gene also exhibit wavy hair coat and curly whiskers