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FLASH GENE

Symbol

VAMP3

contributors: mct - updated : 28-03-2018

HGNC name	vesicle-associated membrane protein 3 (cellubrevin)
HGNC id	12644

FLASH GENE DNA RNA EXPRESSION PROTEIN DISORDER ANIMAL & CELL MODELS

ASSOCIATED DISORDERS

corresponding disease(s)

Other morbid association(s)

Type Gene Modification Chromosome rearrangement Protein expression Protein Function constitutional     --other   silencing inhibits cell adhesion to laminin and effectively reduced cell motility constitutional     --over   protects cardiac glucose metabolism under conditions of impaired insulin sensitivity

Susceptibility

Variant & Polymorphism

Candidate gene

Marker

Therapy target

ANIMAL & CELL MODELS

Vamp3-/- mice had less platelet-associated Fg, indicating a defect in Fg uptake/storage