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FLASH GENE
Symbol VAMP3 contributors: mct - updated : 28-03-2018
HGNC name vesicle-associated membrane protein 3 (cellubrevin)
HGNC id 12644
ASSOCIATED DISORDERS
corresponding disease(s)
Other morbid association(s)
TypeGene ModificationChromosome rearrangementProtein expressionProtein Function
constitutional     --other  
silencing inhibits cell adhesion to laminin and effectively reduced cell motility
constitutional     --over  
protects cardiac glucose metabolism under conditions of impaired insulin sensitivity
Susceptibility
Variant & Polymorphism
Candidate gene
Marker
Therapy target
ANIMAL & CELL MODELS
  • Vamp3-/- mice had less platelet-associated Fg, indicating a defect in Fg uptake/storage