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FLASH GENE
Symbol PLAU contributors: mct - updated : 12-06-2017
HGNC name plasminogen activator, urokinase
HGNC id 9052
ASSOCIATED DISORDERS
corresponding disease(s)
Other morbid association(s)
TypeGene ModificationChromosome rearrangementProtein expressionProtein Function
tumoral     --low  
could suppress tumor growth
Susceptibility
  • to Alzheimer disease
  • to myocardial infarction (MI)
  • Variant & Polymorphism other
  • polymorphism increasing the risk of Alzheimer disease
  • rs4065 might be a previously unknown genetic risk factor for MI
  • Candidate gene
    Marker
  • can be a diagnostic and prognostic biomarker in in head and neck squamous cell carcinoma (HNSCC)
  • Therapy target
    ANIMAL & CELL MODELS