Selected-GenAtlas references	SOURCE	GeneCards	NCBI Gene	Swiss-Prot	Orphanet	Ensembl
	HGNC	UniGene	Nucleotide	OMIM		UCSC

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FLASH GENE

Symbol

NDRG1

contributors: mct - updated : 31-01-2016

HGNC name	N-myc downstream regulated 1
HGNC id	7679

FLASH GENE DNA RNA EXPRESSION PROTEIN DISORDER ANIMAL & CELL MODELS

ASSOCIATED DISORDERS

corresponding disease(s)

CMT4D

related resource

Mutation Database of Inherited Peripheral Neuropathies

Other morbid association(s)

Type Gene Modification Chromosome rearrangement Protein expression Protein Function tumoral     --low   in colorectal neoplasmand in renal carcinoma tumoral     --over   associated with angiogenesis and may be a poor prognostic indicator in women with cervical adenocarcinoma tumoral fusion       NDRG1-ERG fusion in prostate carcinoma is predicted to encode a chimeric protein tumoral     --low   in glioma constitutional     --over   led to decreased expression of the Wnt-responsive gene, CCND1 which drives cell cycle progression

Susceptibility

Variant & Polymorphism

Candidate gene
Marker	could be developed as a marker contributing to diagnosis and evaluating prognosis in gastric cancer
Therapy target
	System Type Disorder Pubmed cancer digestive stomach potential therapeutic target of gastric cancer

ANIMAL & CELL MODELS

being up-regulated in N-Myc knockout mouse embryos