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FLASH GENE

Symbol

TSNAX

contributors: mct/np - updated : 30-12-2015

HGNC name	translin-associated factor X
HGNC id	12380

FLASH GENE DNA RNA EXPRESSION PROTEIN DISORDER ANIMAL & CELL MODELS

ASSOCIATED DISORDERS

corresponding disease(s)

Other morbid association(s)

Type Gene Modification Chromosome rearrangement Protein expression Protein Function constitutional   translocation     translocation t(1;11) (q42.1;q14.3) in a family of patients affeced by schizophrenia constitutional   translocation     five speciesof intergenic splicing, one yielding a fusion protein TSNAX/DISC1 tumoral fusion       chimeric TSNAX-DISC1 occurred significantly upregulated in multiple endometrial carcinoma samples

Susceptibility

to bipolar spectrum disorder to autism spectrum disorders

Variant & Polymorphism other	polymorphisms increasing the risk of bipolar spectrum disorder
	deleted in autism spectrum disorders (Williams 2009)

Candidate gene

Marker

Therapy target

ANIMAL & CELL MODELS