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FLASH GENE
Symbol TIMM17B contributors: - updated : 03-05-2005
HGNC name translocase of inner mitochondrial membrane 17 homolog B (yeast)
HGNC id 17310
PROTEIN
PHYSICAL PROPERTIES Hydrophobic
STRUCTURE
motifs/domains
four hydrophobic membrane-spanning segments
HOMOLOGY
interspecies homolog to murine Timm17b
homolog to Drosophile Tim17b1
homolog to C.elegans E04A4.5
intraspecies homolog to TIMM17A
Homologene
FAMILY TIM17/TIM22/TIM23 family
CATEGORY enzyme , transport channel
SUBCELLULAR LOCALIZATION     intracellular
intracellular,cytoplasm,organelle,mitochondria,inner
basic FUNCTION
  • translocating nuclear-encoded proteins into the mitochondrion
  • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS mitochondrial transport
    PATHWAY
    metabolism
    signaling
    a component
  • forming part of the TIM23 receptor complex consisting of at least three different proteins TIM17, TIM23 and TIM44 (forming 2 distinct 110-kD complexes)
  • INTERACTION
    DNA
    RNA
    small molecule
    protein
  • TIMM17A
  • TIMM17B
  • TIMM23
  • TIMM44
  • cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS