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FLASH GENE
Symbol TIMM17B contributors: - updated : 03-05-2005
HGNC name translocase of inner mitochondrial membrane 17 homolog B (yeast)
HGNC id 17310
RNA
TRANSCRIPTS type messenger
EXPRESSION
Type ubiquitous
constitutive of
   expressed in (based on citations)
organ(s)
SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
Cardiovascularheart   highly
Digestiveliver   lowly
Endocrinepancreas   lowly
Nervousbrain   moderately
Reproductivemale systemprostate  moderately
Urinarykidney   lowly
tissue
SystemTissueTissue level 1Tissue level 2LevelPubmedSpeciesStageRna symbol
Epithelialsecretoryglandularendocrine 
Epithelialsecretoryglandularexocrine 
Muscularstriatumskeletal  
cell lineage
cell lines
fluid/secretion
at STAGE
physiological period pregnancy
Text placenta lowly
PROTEIN
PHYSICAL PROPERTIES Hydrophobic
STRUCTURE
motifs/domains
four hydrophobic membrane-spanning segments
HOMOLOGY
interspecies homolog to murine Timm17b
homolog to Drosophile Tim17b1
homolog to C.elegans E04A4.5
intraspecies homolog to TIMM17A
Homologene
FAMILY TIM17/TIM22/TIM23 family
CATEGORY enzyme , transport channel
SUBCELLULAR LOCALIZATION     intracellular
intracellular,cytoplasm,organelle,mitochondria,inner
basic FUNCTION
  • translocating nuclear-encoded proteins into the mitochondrion
  • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS mitochondrial transport
    PATHWAY
    metabolism
    signaling
    a component
  • forming part of the TIM23 receptor complex consisting of at least three different proteins TIM17, TIM23 and TIM44 (forming 2 distinct 110-kD complexes)
  • INTERACTION
    DNA
    RNA
    small molecule
    protein
  • TIMM17A
  • TIMM17B
  • TIMM23
  • TIMM44
  • cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS