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FLASH GENE
Symbol CDS2 contributors: npt/mct - updated : 28/10/2008
HGNC name CDP-diacylglycerol synthase (phosphatidate cytidylyltransferase) 2
HGNC id 1801
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
  • nine transmembrane domains
  • HOMOLOGY
    interspecies homolog to Drosophila cds
    homolog to murine Cds2
    homolog to C.elegans c33h5.18
    homolog to Drosophila cdp
    intraspecies homolog to CDS1
    Homologene
    FAMILY
  • CDS family
  • CATEGORY enzyme
    SUBCELLULAR LOCALIZATION     intracellular
    intracellular,cytoplasm,organelle,mitochondria,inner
    intracellular,cytoplasm,organelle,mitochondria,matrix
    intracellular,cytoplasm,organelle,membrane
    intracellular,cytoplasm,organelle,endoplasmic reticulum
    text matrix side of the inner mitochondrial membrane
    basic FUNCTION
  • converting phosphatidic acid in CDP (cytidine diphosphate) DAG (dicylglycerol) regulator of cellular phosphatidylinositol content
  • be involved in the synthesis of phosphatidylglycerol and cardiolipin and the cytoplasmic side of the endoplasmic reticulum where it functions in phosphatidylinositol biosynthesis
  • required for phototransduction
  • CELLULAR PROCESS cell organization/biogenesis
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism lipid/lipoprotein
    signaling signal transduction
  • involved in phosphoinositide mediated signaling pathway, phospholipid biosynthesis
  • a component
    INTERACTION
    DNA
    RNA
    small molecule metal binding,
  • Mg2+
  • protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS