basic FUNCTION
| transcriptional corepressor recruited by MEF2 |
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binds specifically to the activated form of calcineurin and inhibits calcineurin-mediated signal transduction |
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recruiting chromatin-modifying enzymes, both histone deacetylases and a histone methyltransferase, to repress MEF2 transcriptional activity |
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recruited to promoters through its interactions with DNA sequence-specific-binding protein MEF2 |
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implicated in regulation of neurotransmitter endocytosis in neuronal cells and muscle cell development |
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recruiting SUV39H1 and repressing transcriptional activity |
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inhibits TP53 function on chromatin in the quiescent state |
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is a functional member of the human HUCA complex |