Selected-GenAtlas references SOURCE GeneCards NCBI Gene Swiss-Prot Ensembl
HGNC UniGene Nucleotide OMIM UCSC
Home Page
FLASH GENE
Symbol EPGN contributors: mct/npt - updated : 18/11/2008
HGNC name epithelial mitogen homolog (mouse)
HGNC id 17470
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
  • two hydrophobic regions, corresponding to a putative signal sequence and transmembrane domain
  • a core of amino acids encompassing six cysteine residues and two putative N-linked glycosylation sites
    • conjugated GlycoP
    HOMOLOGY
    Homologene
    FAMILY
  • EGF superfamily
    • CATEGORY signaling growth factor
    SUBCELLULAR LOCALIZATION     plasma membrane
    basic FUNCTION
  • might represent the last EGF-like growth factor and define a category of low affinity ligands, whose bioactivity differs from the more extensively studied high affinity ligands
  • having ability to promote the growth of epithelial cells
    • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
  • ligand of ErbB receptors
    • cell & other
    REGULATION
    ASSOCIATED DISORDERS
    corresponding disease(s)
    Susceptibility
    Variant & Polymorphism
    Candidate gene
    Marker
    Therapy target
    ANIMAL & CELL MODELS