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FLASH GENE

Symbol

HEMK1

contributors: KTN/NPT - updated : 24/11/2008

HGNC name	HemK methyltransferase family member 1
HGNC id	24923

FLASH GENE DNA RNA EXPRESSION PROTEIN DISORDER ANIMAL & CELL MODELS

PROTEIN

PHYSICAL PROPERTIES

STRUCTURE

motifs/domains

HOMOLOGY

interspecies	homolog to murine Hemk1 (77.8 pc)
	homolog to dog HEMK1 (85.2 pc)
	homolog to cow HEMK1 (82.2 pc)
	homolog to rattus Hemk1 (79 pc)
	homolog to chicken HEMK1 (58.4 pc)

Homologene

FAMILY

hemK family

CATEGORY

enzyme

SUBCELLULAR LOCALIZATION

intracellular

basic FUNCTION	acting as an N-methyltransferase
	methylating the glutamine residue in the GGQ tripeptide motif of HMRF1L

CELLULAR PROCESS

nucleotide, chromatin organization, methylation

PHYSIOLOGICAL PROCESS

PATHWAY

metabolism

signaling

a component

INTERACTION

DNA

binding

RNA

small molecule

protein

cell & other

REGULATION

ASSOCIATED DISORDERS

ANIMAL & CELL MODELS