Selected-GenAtlas references SOURCE GeneCards NCBI Gene Swiss-Prot Ensembl
HGNC UniGene Nucleotide OMIM UCSC
Home Page
FLASH GENE
Symbol HEMK1 contributors: KTN/NPT - updated : 24/11/2008
HGNC name HemK methyltransferase family member 1
HGNC id 24923
DNA
TYPE functioning gene
STRUCTURE 15.51 kb     11 Exon(s)
MAPPING cloned Y linked N status confirmed
RNA
TRANSCRIPTS type messenger
identificationnb exonstypebpproduct
ProteinkDaAAspecific expressionYearPubmed
11 - 5862 38.1 338 - -
EXPRESSION
Type
   expressed in (based on citations)
organ(s)
SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
Digestivesalivary gland   highly
Endocrinethyroid   highly
Lymphoid/Immunelymph node   predominantly
 thymus    
Reproductivefemale systemuteruscervix moderately
Urinarykidney   moderately
cell lineage
cell lines
fluid/secretion
at STAGE
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
HOMOLOGY
interspecies homolog to murine Hemk1 (77.8 pc)
homolog to dog HEMK1 (85.2 pc)
homolog to cow HEMK1 (82.2 pc)
homolog to rattus Hemk1 (79 pc)
homolog to chicken HEMK1 (58.4 pc)
Homologene
FAMILY
  • hemK family
  • CATEGORY enzyme
    SUBCELLULAR LOCALIZATION     intracellular
    basic FUNCTION
  • acting as an N-methyltransferase
  • methylating the glutamine residue in the GGQ tripeptide motif of HMRF1L
  • CELLULAR PROCESS nucleotide, chromatin organization, methylation
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA binding
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS