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FLASH GENE
Symbol ENTPD8 contributors: npt/ - updated : 22-11-2005
HGNC name ectonucleoside triphosphate diphosphohydrolase 8
HGNC id 24860
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
HOMOLOGY
interspecies homolog to murine Entpd8
Homologene
FAMILY
  • GDA1/CD39 NTPase family
  • CATEGORY enzyme
    SUBCELLULAR LOCALIZATION     plasma membrane
    basic FUNCTION
  • responsible for the major ectonucleotidase activity in liver
  • involved in the regulation of bile secretion and/or nucleoside salvage (Fausther 2007)
  • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism purine/pyrimidine
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS