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FLASH GENE
Symbol RNF138 contributors: mct/npt - updated : 21-05-2008
HGNC name ring finger protein 138
HGNC id 17765
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
  • a RING finger domain
    • HOMOLOGY
    Homologene
    FAMILY
  • zinc finger family
    • CATEGORY enzyme
    SUBCELLULAR LOCALIZATION     intracellular
    intracellular,nucleus
    basic FUNCTION
  • having E3 ubiquitin ligase activity
  • nemo-like kinase (NLK)-associated ring finger protein that regulates the ubiquitylation and degradation of T
  • functioning as a novel ubiquitin-ligase to suppress the Wnt-beta-catenin signalingcell factor/lymphoid enhancer factor (TCF/LEF)
    • CELLULAR PROCESS protein, degradation
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA binding
    RNA
    small molecule metal binding,
  • ion Zn2+
    • protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS