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FLASH GENE
Symbol ATP6V0E2 contributors: - updated : 31-08-2007
HGNC name ATPase, H+ transporting V0 subunit E
HGNC id 21723
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
  • C-terminal region contains YVRF
  • a potential YXXØ motif that is not present in ATP6V0E1
    • HOMOLOGY
    interspecies homolog to murine Atp6v0e2
    ortholog to yeast Vma9p
    Homologene
    FAMILY V-ATPase E subunit family
    CATEGORY enzyme , transport carrier
    SUBCELLULAR LOCALIZATION     plasma membrane
    basic FUNCTION
  • may play an important role in the intracellular localization and activity of H+-ATPases
  • vacuolar atpase is responsible for acidifying a variety of intracellular compartment
    • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    text proton
    PATHWAY
    metabolism
    signaling
    a component at least 10 subunits
    INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    corresponding disease(s)
    Susceptibility
    Variant & Polymorphism
    Candidate gene
    Marker
    Therapy target
    ANIMAL & CELL MODELS