| basic FUNCTION
| may be promoting clustering and fusion of late endosomes and lysosomes |
|
modulating the transforming growth factor-beta response by coupling the transforming growth factor-beta receptor complex to the Smad pathway |
|
regulating the balance of SMAD2 and SMAD3 signaling by localizing SMAD4 intracellularly, thus contributing to cellular specificity of TGF-beta transcriptional responses |
|
TBC1D15 and and VPS39 regulate lysosomal morphology and play a role in maintaining growth factor dependence  |
|
with TGFBRAP1, are nonredundant and essentially |
|
required for early embryonic development |
|
cytoplasmic protein involved in lysosomal processing as a novel interactor with Merkel cell polyomavirus large T (LT) oncoprotein |
