basic FUNCTION
| may be promoting clustering and fusion of late endosomes and lysosomes |
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modulating the transforming growth factor-beta response by coupling the transforming growth factor-beta receptor complex to the Smad pathway |
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regulating the balance of SMAD2 and SMAD3 signaling by localizing SMAD4 intracellularly, thus contributing to cellular specificity of TGF-beta transcriptional responses |
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TBC1D15 and and VPS39 regulate lysosomal morphology and play a role in maintaining growth factor dependence  |
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with TGFBRAP1, are nonredundant and essentially |
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required for early embryonic development  |
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cytoplasmic protein involved in lysosomal processing as a novel interactor with Merkel cell polyomavirus large T (LT) oncoprotein  |