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FLASH GENE
Symbol TASP1 contributors: mct - updated : 11-12-2006
HGNC name taspase, threonine aspartase, 1
HGNC id 15859
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
  • asparaginase 2 homology domain
    • mono polymer heteromer , dimer
    HOMOLOGY
    interspecies homolog to Drosophila CG5241
    Homologene
    FAMILY
  • asparaginase family
  • Ntn-hydrolase family
    • CATEGORY enzyme
    SUBCELLULAR LOCALIZATION     intracellular
    intracellular,cytoplasm
    basic FUNCTION
  • cleaving specific substrates following aspartate residues
  • required for proper HOX gene expression and for cleavage of MLL and TFIIA
    • CELLULAR PROCESS protein, degradation
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
  • MLL
  • interacting wit GTF2A1
    • cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS