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FLASH GENE
Symbol TASP1 contributors: mct - updated : 11-12-2006
HGNC name taspase, threonine aspartase, 1
HGNC id 15859
RNA
TRANSCRIPTS type messenger
text several alternate transcripts
identificationnb exonstypebpproduct
ProteinkDaAAspecific expressionYearPubmed
14 - 2368 - 420 - -
EXPRESSION
Type widely
constitutive of
   expressed in (based on citations)
organ(s)
SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
Digestiveesophagus   highly
Endocrineneuroendocrinepituitary  highly
Reproductivefemale systemovary   
Respiratoryrespiratory tractlarynx  highly
cell lineage
cell lines
fluid/secretion
at STAGE
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
  • asparaginase 2 homology domain
  • mono polymer heteromer , dimer
    HOMOLOGY
    interspecies homolog to Drosophila CG5241
    Homologene
    FAMILY
  • asparaginase family
  • Ntn-hydrolase family
  • CATEGORY enzyme
    SUBCELLULAR LOCALIZATION     intracellular
    intracellular,cytoplasm
    basic FUNCTION
  • cleaving specific substrates following aspartate residues
  • required for proper HOX gene expression and for cleavage of MLL and TFIIA
  • CELLULAR PROCESS protein, degradation
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
  • MLL
  • interacting wit GTF2A1
  • cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS