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FLASH GENE
Symbol SCAF1 contributors: npt - updated : 25-07-2005
HGNC name SR-related CTD-associated factor 1
HGNC id 30403
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
  • one SR-rich domain
  • one CTD-binding domain
    • HOMOLOGY
    interspecies homolog to rattus A1 gene
    Homologene
    FAMILY
  • Ser/Arg rich family
  • splicing factor SR family
    • CATEGORY regulatory
    SUBCELLULAR LOCALIZATION     intracellular
    intracellular,cytoplasm,organelle,mitochondria
    basic FUNCTION
  • may be playing an important role in regulation of brain function and neural differentiation
    • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    activated by estrogens, androgens ans glucocortico
    ds (in cancer lines)
    ASSOCIATED DISORDERS
    corresponding disease(s)
    Other morbid association(s)
    TypeGene ModificationChromosome rearrangementProtein expressionProtein Function
    tumoral     --over  
    in ovarian cancer (more agressive)
    Susceptibility
    Variant & Polymorphism
    Candidate gene
    Marker
    Therapy target
    ANIMAL & CELL MODELS