Selected-GenAtlas references SOURCE GeneCards NCBI Gene Swiss-Prot Ensembl
HGNC UniGene Nucleotide OMIM UCSC
Home Page
FLASH GENE
Symbol SCAF1 contributors: npt - updated : 25-07-2005
HGNC name SR-related CTD-associated factor 1
HGNC id 30403
RNA
TRANSCRIPTS type messenger
identificationnb exonstypebpproduct
ProteinkDaAAspecific expressionYearPubmed
1 - 4207 139 1312 - -
EXPRESSION
Type ubiquitous
constitutive of
   expressed in (based on citations)
organ(s)
SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
Digestiveintestinesmall intestine  highly
Lymphoid/Immunespleen    
Nervousbrain   highly
Skin/Tegumentskin    
cell lineage
cell lines
fluid/secretion
at STAGE
physiological period fetal
Text brain and liver highly
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
  • one SR-rich domain
  • one CTD-binding domain
  • HOMOLOGY
    interspecies homolog to rattus A1 gene
    Homologene
    FAMILY
  • Ser/Arg rich family
  • splicing factor SR family
  • CATEGORY regulatory
    SUBCELLULAR LOCALIZATION     intracellular
    intracellular,cytoplasm,organelle,mitochondria
    basic FUNCTION
  • may be playing an important role in regulation of brain function and neural differentiation
  • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    activated by estrogens, androgens ans glucocortico
    ds (in cancer lines)
    ASSOCIATED DISORDERS
    corresponding disease(s)
    Other morbid association(s)
    TypeGene ModificationChromosome rearrangementProtein expressionProtein Function
    tumoral     --over  
    in ovarian cancer (more agressive)
    Susceptibility
    Variant & Polymorphism
    Candidate gene
    Marker
    Therapy target
    ANIMAL & CELL MODELS