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FLASH GENE
Symbol AGTPBP1 contributors: - updated : 13-10-2006
HGNC name ATP/GTP binding protein 1
HGNC id 17258
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
  • one zinc peptide domain
  • nuclear localization signal (NLS)
  • ATP/GTP-binding motif of the P loop type
  • one leucine zipper
  • four consensus phosphoregulation sites for tyrosine kinase
  • HOMOLOGY
    interspecies ortholog to murine Agtpbp1
    intraspecies homolog to AEBP1
    Homologene
    FAMILY
    CATEGORY enzyme
    SUBCELLULAR LOCALIZATION     intracellular
    intracellular,nucleus
    basic FUNCTION
  • zinc carboxypeptidase may contribute to nuclear signaling events in differentiating and regenerating neurons
  • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    text involved in axonal regeneration
    PATHWAY
    metabolism
    signaling sensory transduction/vision
    a component
    INTERACTION
    DNA
    RNA
    small molecule metal binding, cofactor,
    zinc Zn2+
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    corresponding disease(s) PCDRS
    Susceptibility
    Variant & Polymorphism
    Candidate gene
    Marker
    Therapy target
    ANIMAL & CELL MODELS
    mouse Purkinje cell degeneration (pcd)