basic FUNCTION
| PDZ-domain binding activity |
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TBC domain-containing protein that regulates microvillar subdomains and structure |
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GTPase-activating protein specific for RAB27A |
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TBC1D10A, TBC1D10C regulate exosome secretion in a catalytic activity-dependent manner |
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apical microvillar protein, regulating ARF6-dependent membrane trafficking |
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regulates membrane trafficking both by stabilizing ARF6-GTP and by inhibiting the recycling of membrane through the tubular endosome by decreasing RAB8A-GTP levels |
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TBC1D10A, CYTH2 regulate endocytosis at distinct stages |
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TBC1D10A, TBC1D10B, TBC1D10C, having the physiological and pathological functions such as melanosome transport, exosome secretion, and T-cell activation |