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FLASH GENE
Symbol CD3EAP contributors: - updated : 28-03-2006
HGNC name CD3e antigen, epsilon polypeptide associated protein
HGNC id 24219
EXPRESSION
Type restricted
constitutive of
   expressed in (based on citations)
organ(s)
cell lineage
cell lines
fluid/secretion
at STAGE
cell cycle     cell cycle, interphase, M
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
a glycine-arginine-phenylalanine rich putative nucleotide interaction domain and an alternating basic/acid region,a phosphorylation site
conjugated PhosphoP
HOMOLOGY
Homologene
FAMILY
CATEGORY regulatory
SUBCELLULAR LOCALIZATION     plasma membrane
    intracellular
intracellular,nucleus
text
  • fibrillar centres of the nucleolus in interphase
  • at nucleolus organizer regions of the chromosome during mitosis
    • basic FUNCTION
  • activating signals upon TCR signalization
  • involved in nucleolar function
    • CELLULAR PROCESS protein, translation regulation
    PHYSIOLOGICAL PROCESS development
    text thymus development
    PATHWAY
    metabolism
    signaling signal transduction
    signaling pathway via CD3 epsilon-containing TCR signaling molecule
    a component componentof a preformed TCR complex
    INTERACTION
    DNA binding
    RNA binding
    small molecule
    protein
  • colocolizing and associating with RNA polymerase I transcription initiation factor,UBF/NOR90,throughout the cell cycle
  • interacting with CD3 epsilon
    • cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS