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FLASH GENE
Symbol CD3EAP contributors: - updated : 28-03-2006
HGNC name CD3e antigen, epsilon polypeptide associated protein
HGNC id 24219
RNA
TRANSCRIPTS type messenger
EXPRESSION
Type restricted
constitutive of
   expressed in (based on citations)
organ(s)
cell lineage
cell lines
fluid/secretion
at STAGE
cell cycle     cell cycle, interphase, M
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
a glycine-arginine-phenylalanine rich putative nucleotide interaction domain and an alternating basic/acid region,a phosphorylation site
conjugated PhosphoP
HOMOLOGY
Homologene
FAMILY
CATEGORY regulatory
SUBCELLULAR LOCALIZATION     plasma membrane
    intracellular
intracellular,nucleus
text
  • fibrillar centres of the nucleolus in interphase
  • at nucleolus organizer regions of the chromosome during mitosis
    • basic FUNCTION
  • activating signals upon TCR signalization
  • involved in nucleolar function
    • CELLULAR PROCESS protein, translation regulation
    PHYSIOLOGICAL PROCESS development
    text thymus development
    PATHWAY
    metabolism
    signaling signal transduction
    signaling pathway via CD3 epsilon-containing TCR signaling molecule
    a component componentof a preformed TCR complex
    INTERACTION
    DNA binding
    RNA binding
    small molecule
    protein
  • colocolizing and associating with RNA polymerase I transcription initiation factor,UBF/NOR90,throughout the cell cycle
  • interacting with CD3 epsilon
    • cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS