basic FUNCTION
| having essential roles in the regulation of Ige production and in the differentiation of B-cells (it is a B-cell-specific antigen) |
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low affinity receptor for IgE and in B cells has been proposed to play a role in the regulation of IgE synthesis |
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FCER2-mediated signal transduction pathways in human B cells and human monocytes are different |
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low-affinity receptor for immunoglobulin (Ig)E and plays important roles in the regulation of IgE responses ( |
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FCER2-bound IgE augments and dominates recall responses through naive B cells |
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when expressed on B cells, FCER2 appears to play a role in regulation of IgE synthesis |
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role for FCER2 likely in many species as a receptor for potentially pathogenic microorganisms as well as IgE |
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