basic FUNCTION
| involved in the compaction of chromatin |
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controls the growth of normal and tumor-derived prostate cells by repressing the CDKN2A |
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chromobox protein causally linked to cancer development and may help explain the low frequency of CDKN2A mutations observed in human follicular lymphoma |
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acts as an oncogene in the carcinogenesis and progression of gastric cancer |
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may regulate tumorigenesis, cell migration and cancer metastasis partially via CDKN2A regulatory pathway |
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within the polycomb repressive complex 1 binds to CDKN2BAS and both CBX7 and CDKN2BAS are found at elevated levels in prostate cancer tissues |
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necessary for recruitment of RNF2 to chromatin, whereas RYBP enhances the PRC1 enzymatic activity |
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negative role of CBX7 in the control of adipocyte cell growth and differentiation |
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is a polycomb protein that participates in the formation of polycomb repressive complex 1 |
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critical role of CBX7 in cancer progression |
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transcriptional repressor involved in the regulation of cell proliferation and senescence |
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negatively regulates the proliferation, viability, chemoresistance, and migration of pancreatic cancer cells |
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