Selected-GenAtlas references SOURCE GeneCards NCBI Gene Swiss-Prot Ensembl
HGNC UniGene Nucleotide OMIM UCSC
Home Page
FLASH GENE
Symbol CD164 contributors: npt/mct - updated : 24/10/2008
HGNC name CD164 antigen, sialomucin
HGNC id 1632
DNA
TYPE functioning gene
STRUCTURE 15.92 kb     6 Exon(s)
10 Kb 5' upstream gene genomic sequence study
MAPPING cloned Y linked N status provisional
RNA
TRANSCRIPTS type messenger
identificationnb exonstypebpproduct
ProteinkDaAAspecific expressionYearPubmed
6 - 3026 20 197 - Chan, Forde (2007)
- splicing - - - - Chan
- splicing - - - - Chan
EXPRESSION
Type ubiquitous
   expressed in (based on citations)
organ(s)
SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
Digestiveintestinesmall intestine   
 intestinelarge intestinecolon  
Endocrinethyroid    
Lymphoid/Immunethymus   highly
Reproductivefemale systembreastmammary gland highly
Respiratoryrespiratory tracttrachea  highly
tissue
SystemTissueTissue level 1Tissue level 2LevelPubmedSpeciesStageRna symbol
Epithelialsecretoryglandularendocrine 
cell lineage CD34+ B cell precursors and in maturing erythroid cells
cell lines colorectal and pancreatic adenocarcinoma cells
fluid/secretion
at STAGE
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
  • two extracellular mucin domain
  • conjugated GlycoP
    HOMOLOGY
    interspecies homolog to murine Cd164
    homolog to rattus endolyn
    Homologene
    FAMILY
  • CD164 family
  • CATEGORY adhesion , antigen , receptor
    SUBCELLULAR LOCALIZATION extracellular
        plasma membrane
        intracellular
    intracellular,cytoplasm,organelle,membrane
    intracellular,cytoplasm,organelle,endosome
    text type I transmembrane protein
    basic FUNCTION
  • potent regulator of hematopoiesis
  • adhesion receptor that regulates the adhesion of CD34+ cells to bone marrow stroma
  • function as a receptor that regulates stem cell localization to the bone marrow
  • may participate in the localization of prostate cancer cells to the marrow and is further evidence that tumor metastasis and hematopoietic stem cell trafficking may involve similar processes
  • CELLULAR PROCESS cell life, differentiation
    PHYSIOLOGICAL PROCESS
    text cell differentiation, identified by monoclonal antibodies 103B2/9E10 and 105A5
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein associates with CXCR4
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS