basic FUNCTION
| probable pseudophosphatase |
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acting as a protein tyrosine/serine/threonine phosphatase |
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having a role for MK-STYX in regulating the ability of G3BP1 to integrate changes in growth-factor stimulation and environmental stress with the regulation of protein synthesis |
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catalytically inactive phosphatase with homology to the mitogen-activated protein kinase (MAPK) phosphatases |
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regulates mitochondrial outer membrane permeabilization using a distinct mechanism |
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plays a key role in the cellular response to stress |
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STYX and MAPK-STYX (STYXL1), are integral signaling molecules in regulating pathways involved in neuronal developmental processes such as neurite outgrowth |
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very specific role of STYX and STYXL1 for each pseudophosphatase, further highlighting the relevance of these atypical members of DUSP as signaling regulators |