Selected-GenAtlas references | SOURCE | GeneCards | NCBI Gene | Swiss-Prot | Orphanet | Ensembl |
HGNC | UniGene | Nucleotide | OMIM | UCSC |
Home Page |
FLASH GENE |
Symbol | KRT6A | contributors: npt/mct - updated : 26-12-2006 |
HGNC name | keratin 6A |
HGNC id | 6443 |
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Corresponding disease |
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Location | 12q13 Physical location : 52.880.958 - 52.887.181 | ||
Synonym name | |||
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Synonym symbol(s) | K6A, CK6A, K6D,CK6D, CK6C, K6C, KRT6D, KRT6C |
DNA |
TYPE | functioning gene |
SPECIAL FEATURE | component of a cluster |
text | clustered with other type II cytokeratins |
STRUCTURE | 6.22 kb 9 Exon(s) |
10 Kb 5' upstream gene genomic sequence study |
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MAPPING | cloned | Y | linked | N | status | confirmed |
RNA |
TRANSCRIPTS | type | messenger |
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EXPRESSION |
Type | ubiquitous |
constitutive of |
expressed in | (based on citations) | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
organ(s) |
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tissue |
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cells |
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cell lineage
cell lines
| fluid/secretion
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at STAGE |
PROTEIN |
PHYSICAL PROPERTIES
STRUCTURE
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mono polymer | heteromer , dimer |
HOMOLOGY |
interspecies | ortholog to murine Krt2-6a |
homolog to C.elegans F58E10.3 |
Homologene |
FAMILY | |
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CATEGORY | structural protein |
SUBCELLULAR LOCALIZATION | intracellular |
intracellular,cytoplasm,cytoskeleton,intermed filament | |
text | expressed with family members KRT16 and/or KRT17 |
basic FUNCTION |
CELLULAR PROCESS | cell life, proliferation/growth |
cell organization/biogenesis |
PHYSIOLOGICAL PROCESS | development |
text | |
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PATHWAY |
metabolism |
signaling |
a component | |
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INTERACTION |
DNA |
RNA |
small molecule |
protein |
cell & other |
REGULATION |
ASSOCIATED DISORDERS |
corresponding disease(s) | PC112 |
Susceptibility |
Variant & Polymorphism
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Candidate gene
Marker
| Therapy target
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ANIMAL & CELL MODELS |
K6-null mice (Wong,2000) |