Selected-GenAtlas references | SOURCE | GeneCards | NCBI Gene | Swiss-Prot | Ensembl |
HGNC | UniGene | Nucleotide | OMIM | UCSC |
Home Page |
FLASH GENE |
Symbol | ATP5O | contributors: - updated : 18-10-2006 |
HGNC name | ATP synthase, H+ transporting, mitochondrial F1 complex, O subunit (oligomycin sensitivity conferring protein) |
HGNC id | 850 |
|
Location | 21q22.1-q22.2 Physical location : 35.275.757 - 35.288.158 |
Synonym name | |
Synonym symbol(s) | ATPO, OSCP |
EC.number | 3.6.3.14 |
DNA |
TYPE | functioning gene |
STRUCTURE | 12.00 kb 7 Exon(s) |
10 Kb 5' upstream gene genomic sequence study |
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MAPPING | cloned | Y | linked | status | confirmed |
RNA |
TRANSCRIPTS | type | messenger |
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EXPRESSION |
Type | ubiquitous |
constitutive of |
expressed in | (based on citations) | ||||||||||||||||||||||||||||||||||||||||||||||||||
organ(s) |
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tissue |
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cell lineage
cell lines
| fluid/secretion
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at STAGE |
physiological period | fetal |
Text | umbilical cord |
PROTEIN |
PHYSICAL PROPERTIES
STRUCTURE
| |
motifs/domains
|
isoforms | Precursor | a 189 aa mature peptide (20.9 kda) |
HOMOLOGY |
interspecies | homolog to rattus Atp5o (81.7pc) |
homolog to murine Atp5o (82.2pc) |
Homologene |
FAMILY |
CATEGORY | enzyme , transport |
SUBCELLULAR LOCALIZATION | intracellular |
intracellular,cytoplasm,organelle,mitochondria,inner | |
intracellular,cytoplasm,organelle,mitochondria,matrix |
basic FUNCTION | |
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| |
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CELLULAR PROCESS |
PHYSIOLOGICAL PROCESS |
text | |
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PATHWAY |
metabolism | energetic |
signaling |
a component | |
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INTERACTION |
DNA |
RNA |
small molecule |
protein |
cell & other |
REGULATION |
inhibited by | immunomodulatory benzodiazepine Bz-423 (in vitro) |
ASSOCIATED DISORDERS |
corresponding disease(s) |
related resource | MITOP database |
Susceptibility |
Variant & Polymorphism
| |
Candidate gene
Marker
| Therapy target
| for lupus |
| |
ANIMAL & CELL MODELS |