SUBCELLULAR LOCALIZATION
| extracellular
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| intracellular
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| intracellular,cytoplasm,organelle,mitochondria,matrix
|
| intracellular,cytoplasm,cytosolic
|
| intracellular,cytoplasm,cytoskeleton,microtubule
|
| intracellular,nucleus,nucleoplasm
|
basic FUNCTION
| important role in the renal tubular degradation or resorption of APOA1 |
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plays an important role in sperm capacitation possibly providing a link between protein phosphorylation and cholesterol efflux |
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secreted NAXE positively regulates cholesterol efflux from endothelial cells and effective cholesterol efflux is critical for proper angiogenesis |
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encodes two different proteins, which we show to be targeted to the mitochondria (mAIBP) and the cytosol (cAIBP) |
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contributes to mitotic entry and bipolar spindle assembly and may partially control localization, phosphorylation, and activation of both AURKA and PLK1 via NIN during mitotic progression |
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catalyzes the epimerization of NAD(P)HX, thereby avoiding the accumulation of toxic metabolites |
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epimerase essential in the cellular metabolite repair for NADHX and NADPHX |