Selected-GenAtlas references | SOURCE | GeneCards | NCBI Gene | Swiss-Prot | Orphanet | Ensembl |
HGNC | UniGene | Nucleotide | OMIM | UCSC |
Home Page |
FLASH GENE |
Symbol | AGXT | contributors: mct - updated : 01-09-2009 |
HGNC name | alanine-glyoxylate aminotransferase |
HGNC id | 341 |
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Corresponding disease |
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Location | 2q37.3 Physical location : 241.808.161 - 241.818.535 | ||
Synonym name | |||
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Synonym symbol(s) | SPAT, AGXT1, AGT1, TLH6, SPT, PH1, AGT | ||
EC.number | 2.6.1.51, 2.6.1.44 |
DNA |
TYPE | functioning gene |
STRUCTURE | 10.37 kb 11 Exon(s) 1 Copie(s) |
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10 Kb 5' upstream gene genomic sequence study |
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MAPPING | cloned | Y | linked | N | status | confirmed |
RNA |
TRANSCRIPTS | type | messenger |
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EXPRESSION |
Type | restricted |
constitutive of |
expressed in | (based on citations) | ||||||||||||||||||||
organ(s) |
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cell lineage
cell lines
| fluid/secretion
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at STAGE |
PROTEIN |
PHYSICAL PROPERTIES
STRUCTURE
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motifs/domains
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mono polymer | homomer , dimer |
HOMOLOGY |
interspecies | homolog to murine Agset |
homolog to C.elegans t14d7.1 |
Homologene |
FAMILY |
CATEGORY | enzyme |
SUBCELLULAR LOCALIZATION
| intracellular |
intracellular,cytoplasm,organelle,peroxisome | |
text | mitochondrial matrix in some ph1 patients |
basic FUNCTION |
CELLULAR PROCESS |
PHYSIOLOGICAL PROCESS | excretion |
text | glyoxylate detoxication |
PATHWAY |
metabolism | other |
signaling |
glyoxylate cycle pyruvate metabolism |
a component |
INTERACTION |
DNA |
RNA |
small molecule | cofactor, |
protein |
cell & other |
REGULATION |
ASSOCIATED DISORDERS |
corresponding disease(s) | PHXL1 |
related resource | MITOP database |
Susceptibility |
Variant & Polymorphism
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Candidate gene
Marker
| Therapy target
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ANIMAL & CELL MODELS |