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FLASH GENE

Symbol

PRPS2

contributors: - updated : 29-08-2007

HGNC name	phosphoribosyl pyrophosphate synthetase 2
HGNC id	9465

FLASH GENE DNA RNA EXPRESSION PROTEIN DISORDER ANIMAL & CELL MODELS

DNA

TYPE	functioning gene
STRUCTURE	32.00 kb     7 Exon(s)

10 Kb 5' upstream gene genomic sequence study

MAPPING

cloned

Y

linked

status

confirmed

Map	pter - STS - AMELX - PRPS2 - DXF22S4 - GLRA2 - PDHA1 - ZFX - POLA - cen
Authors	Schlessinger (93)

RNA

TRANSCRIPTS	type	messenger

identification nb exons type bp product Protein kDa AA specific expression Year Pubmed variant 1 - - 2518 - 321 - Ishijima variant 2 - - 2509 - 318 - Ishijima

EXPRESSION

Type	ubiquitous

constitutive of

expressed in	(based on citations)
organ(s)	System Organ level 1 Organ level 2 Organ level 3 Organ level 4 Level Pubmed Species Stage Rna symbol Endocrine parathyroid       highly Reproductive male system testis     highly Urinary bladder       highly

cell lineage

cell lines

fluid/secretion

at STAGE

PROTEIN

PHYSICAL PROPERTIES

STRUCTURE

motifs/domains

HOMOLOGY

interspecies

homolog to murine Prps1

intraspecies

homolog to PRPS1

Homologene

FAMILY

ribose phosphate phosphokinase family

CATEGORY

enzyme

SUBCELLULAR LOCALIZATION

basic FUNCTION

unknown

CELLULAR PROCESS

PHYSIOLOGICAL PROCESS

PATHWAY

metabolism

nucleic

signaling

nucleotide

a component

INTERACTION

DNA

RNA

small molecule

protein

cell & other

REGULATION

activated by

by magnesium and inorganic phosphate

ASSOCIATED DISORDERS

ANIMAL & CELL MODELS