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FLASH GENE
Symbol ZNF205 contributors: npt/mct - updated : 06-05-2009
HGNC name zinc finger protein 205
HGNC id 12996
Location 16p13.3      Physical location : 3.162.562 - 3.170.516
Synonym name
  • zinc finger protein 210
  • regulator of heat-induced transcription
    • Synonym symbol(s) ZNF210, Zfp13, RHIT
    DNA
    TYPE functioning gene
    STRUCTURE 7.96 kb     7 Exon(s)
    10 Kb 5' upstream gene genomic sequence study
    MAPPING cloned Y linked N status confirmed
    Map pter - D16S468 - ZNF205 - ZNF200 - D16S3275 - cen
    Authors Deng (98)
    RNA
    TRANSCRIPTS type messenger
    identificationnb exonstypebpproduct
    ProteinkDaAAspecific expressionYearPubmed
    7 - 2077 60.5 554 - Deng (1998)
    7 - 2009 60.5 554 - Deng (1998)
    EXPRESSION
    Type ubiquitous
       expressed in (based on citations)
    organ(s)
    SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
    Cardiovascularheart    
    Digestiveintestinelarge intestinecolon  
    Endocrinepancreas    
    Reproductivefemale systemovary   
     male systemprostate   
     male systemmale genital tract   
    tissue
    SystemTissueTissue level 1Tissue level 2LevelPubmedSpeciesStageRna symbol
    Epithelialsecretoryglandularendocrine 
    Epithelialsecretoryglandularexocrine 
    Muscularstriatumskeletal  
    cell lineage
    cell lines
    fluid/secretion
    at STAGE
    PROTEIN
    PHYSICAL PROPERTIES
    STRUCTURE
    motifs/domains
  • a N terminal KRAB (Krüppel-associated box) domain
  • a DNA-binding domain composed of eight C2H2-type zinc fingers (Iida 2010)
    • conjugated MetalloP
    HOMOLOGY
    Homologene
    FAMILY
  • krueppel C2H2-type zinc-finger protein family
    • CATEGORY transcription factor
    SUBCELLULAR LOCALIZATION     intracellular
    intracellular,nucleus,chromatin/chromosome
    basic FUNCTION
  • acts as a repressor in the heat-induced and age-dependent transcriptional regulation of MPV17L (Iida 2010)
    • CELLULAR PROCESS nucleotide, transcription
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA binding
    RNA
    small molecule metal binding,
  • Zn2+
    • protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS